Mikael Akke : rechercher sur Z-Library

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1

Systematic tuning of fluoro-galectin-3 interactions provides thiodigalactoside derivatives with single digit nM affinity and high selectivity

Peterson, Kristoffer, kumar, rohit, Stenström, Olof, Verma, Priya, Verma, Prashant R, Håkansson, Maria, Kahl-Knutsson, Barbro, Zetterberg, Fredrik, Leffler, Hakon, Akke, Mikael, Logan, Derek Thomas, N

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2017

2

Protein stability and electrostatic interactions between solvent exposed charged side chains

Mikael Akke, Dr. Sture Forsén

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1990

Langue:

english

Fichier:

PDF, 653 KB

english, 1990

3

NMR methods for characterizing microsecond to millisecond dynamics in recognition and catalysis

Journal:

Current Opinion in Structural Biology

Année:

2002

Langue:

english

Fichier:

PDF, 76 KB

english, 2002

4

Quantitative Analysis of Conformational Exchange Contributions to 1 H− 15 N Multiple-Quantum Relaxation Using Field-Dependent Measurements. Time Scale and Structural Characterization of Exchange in a Calmodulin C-Terminal Domain Mutant

Lundström, Patrik, Akke, Mikael

Journal:

Journal of the American Chemical Society

Année:

2004

Langue:

english

Fichier:

PDF, 304 KB

english, 2004

5

Microsecond Protein Dynamics Measured by 13Cα Rotating-Frame Spin Relaxation

Patrik Lundström, Mikael Akke

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 162 KB

english, 2005

6

Carbonyl 13C transverse relaxation measurements to sample protein backbone dynamics

Frans A. A. Mulder, Mikael Akke

Journal:

Magnetic Resonance in Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 888 KB

english, 2003

7

15N NMR assignments of (Cd2+,)2-calbindin D9k and comparison with (Ca2+)2-calbindin D9k. Cadmium as a substitute for calcium in calcium-binding proteins

Mikael Akke, Sture Forsén, Walter J. Chazin

Journal:

Magnetic Resonance in Chemistry

Année:

1993

Langue:

english

Fichier:

PDF, 508 KB

english, 1993

8

Ca2+-Binding in proteins of the calmodulin superfamily:Cooperativity and its molecular basis.

Sture Forsén, Mikael Akke, Sara Linse, Walter Chazin

Journal:

Journal of Inorganic Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 61 KB

english, 1991

9

Unfolding and inactivation of cutinases by AOT and guanidine hydrochloride

Tomas Ternström, Allan Svendsen, Mikael Akke, Patrick Adlercreutz

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2005

Langue:

english

Fichier:

PDF, 290 KB

english, 2005

10

A statistical analysis of NMR spectrometer noise

Halfdan Grage, Mikael Akke

Journal:

Journal of Magnetic Resonance

Année:

2003

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2003

11

Protein loop compaction and the origin of the effect of arginine and glutamic acid mixtures on solubility, stability and transient oligomerization of proteins

Jascha Blobel, Ulrika Brath, Pau Bernadó, Carl Diehl, Lidia Ballester, Alejandra Sornosa, Mikael Akke, Miquel Pons

Journal:

European Biophysics Journal

Année:

2011

Langue:

english

Fichier:

PDF, 582 KB

english, 2011

12

Off-resonance rotating-frame amide proton spin relaxation experiments measuring microsecond chemical exchange in proteins

Patrik Lundström, Mikael Akke

Journal:

Journal of Biomolecular NMR

Année:

2005

Langue:

english

Fichier:

PDF, 540 KB

english, 2005

13

Fractional13C enrichment of isolated carbons using [1-13C]- or [2-13C]-glucose facilitates the accurate measurement of dynamics at backbone Cαand side-chain methyl positions in proteins

Patrik Lundström, Kaare Teilum, Tommy Carstensen, Irina Bezsonova, Silke Wiesner, D. Flemming Hansen, Tomasz L. Religa, Mikael Akke, Lewis E. Kay

Journal:

Journal of Biomolecular NMR

Année:

2007

Langue:

english

Fichier:

PDF, 673 KB

english, 2007

14

Conformational entropy changes upon lactose binding to the carbohydrate recognition domain of galectin-3

Carl Diehl, Samuel Genheden, Kristofer Modig, Ulf Ryde, Mikael Akke

Journal:

Journal of Biomolecular NMR

Année:

2009

Langue:

english

Fichier:

PDF, 623 KB

english, 2009

15

100% complete assignment of non-labile1H,13C, and15N signals for calcium-loaded calbindin D9kP43G

Nur Alia Oktaviani, Renee Otten, Klaas Dijkstra, Ruud M. Scheek, Eva Thulin, Mikael Akke, Frans A. A. Mulder

Journal:

Biomolecular NMR Assignments

Année:

2011

Langue:

english

Fichier:

PDF, 511 KB

english, 2011

16

10.1038/71202

Cavanagh, John, Akke, Mikael

Journal:

Natural Structural Biology

Année:

2000

Langue:

english

Fichier:

PDF, 246 KB

english, 2000

17

Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain

Akke, Mikael, Liu, Jun, Cavanagh, John, Erickson, Harold P., Palmer, Arthur G.

Journal:

Natural Structural Biology

Année:

1998

Fichier:

PDF, 633 KB

1998

18

Signal transduction versus buffering activity in Ca2+–binding proteins

Skelton, Nicholas J., Kördel, Johan, Akke, Mikael, Forsén, Sture, Chazin, Walter J.

Journal:

Natural Structural Biology

Année:

1994

Fichier:

PDF, 901 KB

1994

19

The structure of calcyclin reveals a novel homodimeric fold for S100 Ca2+-binding proteins

Potts, Barbara C. M., Smith, Jarrod, Akke, Mikael, Macke, Thomas J., Okazaki, Katsuo, Hidaka, Hiroyoshi, Case, David A., Chazin, Walter J.

Journal:

Natural Structural Biology

Année:

1995

Fichier:

PDF, 954 KB

1995

20

10.1038/nsb1101-910

Akke, Mikael, Chazin, Walter J.

Journal:

Natural Structural Biology

Année:

2001

Langue:

english

Fichier:

PDF, 701 KB

english, 2001

21

Out of hot water

Journal:

Nature Structural and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 78 KB

english, 2004

22

Letter to the Editor: Sequential1H,15N and13C NMR Assignment of Human Calbindin D28k

Magnus Helgstrand, Christophe Vanbelle, Eva Thulin, Sara Linse, Mikael Akke

Journal:

Journal of Biomolecular NMR

Année:

2004

Langue:

english

Fichier:

PDF, 95 KB

english, 2004

23

Conformational dynamics and thermodynamics of protein–ligand binding studied by NMR relaxation

Journal:

Biochemical Society Transactions

Année:

2012

Langue:

english

Fichier:

PDF, 286 KB

english, 2012

24

Dynamics of the Transition between Open and Closed Conformations in a Calmodulin C-Terminal Domain Mutant

Johan Evenäs, Anders Malmendal, Mikael Akke

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 468 KB

english, 2001

25

Structural Characterization of the Ribosomal P1A−P2B Protein Dimer by Small-Angle X-ray Scattering and NMR Spectroscopy†

Grela, Przemysłw, Helgstrand, Magnus, Krokowski, Dawid, Boguszewska, Aleksandra, Svergun, Dmitri, Liljas, Anders, Bernadó, Pau, Grankowski, Nikodem, Akke, Mikael, Tchórzewski, Marek

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 518 KB

english, 2007

26

High-resolution Solution Structure of Calcium-loaded Calbindin D9k

Johan Kördel, Nicholas J. Skelton, Mikael Akke, Walter J. Chazin

Journal:

Journal of Molecular Biology

Année:

1993

Fichier:

PDF, 1.58 MB

1993

27

Backbone Dynamics ofEscherichia coliRibonuclease HI: Correlations with Structure and Function in an Active Enzyme

Arthur M. Mandel, Mikael Akke, Arthur G. Palmer, III

Journal:

Journal of Molecular Biology

Année:

1995

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1995

28

Solution Structure of (Cd2+)1-calbindin D9kReveals Details of the Stepwise Structural Changes along the Aporarr;(Ca2+)1IIrarr;(Ca2+)2I,IIBinding Pathway

Mikael Akke, Sture Forsén, Walter J. Chazin

Journal:

Journal of Molecular Biology

Année:

1995

Langue:

english

Fichier:

PDF, 4.01 MB

english, 1995

29

Backbone dynamics and energetics of a Calmodulin domain mutant exchanging between closed and open conformations

Johan Evenäs, Sture Forsén, Anders Malmendal, Mikael Akke

Journal:

Journal of Molecular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 451 KB

english, 1999

30

Structural dynamics in the C-terminal domain of calmodulin at low calcium levels

Anders Malmendal, Johan Evenäs, Sture Forsén, Mikael Akke

Journal:

Journal of Molecular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 445 KB

english, 1999

31

15N NMR assignments and chemical shift analysis of uniformly labeled15N calbindin D9k in the apo, (Cd2+)1 and (Ca2+)2 states

Nicholas J. Skelton, Mikael Akke, Johan Ko¨rdell, Eva Thulin, Sture Forse´n, Walter J. Chazin

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 587 KB

english, 1992

32

Nuclear magnetic resonance studies of the internal dynamics in apo, (Cd2+)1 and (Ca2+)2 Calbindin D9k: The rates of amide proton exchange with solvent

Nicholas J. Skelton, Johan Kördel, Mikael Akke, Walter J. Chazin

Journal:

Journal of Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 2.63 MB

english, 1992

33

Compact oleic acid in HAMLET

Jonas Fast, Ann-Kristin Mossberg, Hanna Nilsson, Catharina Svanborg, Mikael Akke, Sara Linse

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 323 KB

english, 2005

34

The Ribosomal Stalk Binds to Translation Factors IF2, EF-Tu, EF-G and RF3 via a Conserved Region of the L12 C-terminal Domain

Magnus Helgstrand, Chandra S. Mandava, Frans A.A. Mulder, Anders Liljas, Suparna Sanyal, Mikael Akke

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2007

35

Differential Responses of the Backbone and Side-Chain Conformational Dynamics in FKBP12 upon Binding the Transition-State Analog FK506: Implications for Transition-State Stabilization and Target Protein Recognition

Ulrika Brath, Mikael Akke

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 510 KB

english, 2009

36

Intramolecular Dynamics of Low Molecular Weight Protein Tyrosine Phosphatase in Monomer–Dimer Equilibrium Studied by NMR: A Model for Changes in Dynamics upon Target Binding

Tomas Åkerud, Eva Thulin, Robert L. Van Etten, Mikael Akke

Journal:

Journal of Molecular Biology

Année:

2002

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2002

37

Conformational exchange of aromatic side chains characterized by L-optimized TROSY-selected13C CPMG relaxation dispersion

Ulrich Weininger, Michal Respondek, Mikael Akke

Journal:

Journal of Biomolecular NMR

Année:

2012

Langue:

english

Fichier:

PDF, 342 KB

english, 2012

38

13C relaxation experiments for aromatic side chains employing longitudinal- and transverse-relaxation optimized NMR spectroscopy

Ulrich Weininger, Carl Diehl, Mikael Akke

Journal:

Journal of Biomolecular NMR

Année:

2012

Langue:

english

Fichier:

PDF, 501 KB

english, 2012

39

Molecular basis for co-operativity in Ca2+ binding to calbindin D9k: 1H nuclear magnetic resonance studies of (Cd2+)1-bovine calbindin D9k

Mikael Akke, Sture Forsén, Walter J. Chazin

Journal:

Journal of Molecular Biology

Année:

1991

Langue:

english

Fichier:

PDF, 4.26 MB

english, 1991

40

Structure and Dynamics of Ribosomal Protein L12: An Ensemble Model Based on SAXS and NMR Relaxation

Bernadó, Pau, Modig, Kristofer, Grela, Przemysław, Svergun, Dmitri I., Tchorzewski, Marek, Pons, Miquel, Akke, Mikael

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 595 KB

english, 2010

41

pKa Values for the Unfolded State under Native Conditions Explain the pH-Dependent Stability of PGB1

Lindman, Stina, Bauer, Mikael C., Lund, Mikael, Diehl, Carl, Mulder, Frans A.A., Akke, Mikael, Linse, Sara

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 467 KB

english, 2010

42

Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3

Diehl, Carl, Engström, Olof, Delaine, Tamara, Håkansson, Maria, Genheden, Samuel, Modig, Kristofer, Leffler, Hakon, Ryde, Ulf, Nilsson, Ulf J., Akke, Mikael

Journal:

Journal of the American Chemical Society

Année:

2010

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2010

43

NMR order parameters and free energy: an analytical approach and its application to cooperative calcium(2+) binding by calbindin D9k

Akke, Mikael, Brueschweiler, Rafael, Palmer, Arthur G.

Journal:

Journal of the American Chemical Society

Année:

1993

Langue:

english

Fichier:

PDF, 270 KB

english, 1993

44

Dynamics of Ribonuclease H: Temperature Dependence of Motions on Multiple Time Scales †

Mandel, Arthur M., Akke, Mikael, Palmer, Arthur G.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 612 KB

english, 1996

45

Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected nitrogen-15 NMR spectroscopy

Koerdel, Johan, Skelton, Nicholas J., Akke, Mikael, Palmer, Arthur G., Chazin, Walter J.

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 2.00 MB

english, 1992

46

Off-resonance rotating-frame relaxation dispersion experiment for13C in aromatic side chains using L-optimized TROSY-selection

Weininger, Ulrich, Brath, Ulrika, Modig, Kristofer, Teilum, Kaare, Akke, Mikael

Journal:

Journal of Biomolecular NMR

Année:

2014

Langue:

english

Fichier:

PDF, 367 KB

english, 2014

47

Effects of ion binding on the backbone dynamics of calbindin D9k determined by nitrogen-15 NMR relaxation

Akke, Mikael, Skelton, Nicholas J., Kordel, Johan, Palmer, Arthur G., Chazin, Walter J.

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 2.30 MB

english, 1993

48

Characterization of Chemical Exchange Using Residual Dipolar Coupling

Igumenova, Tatyana I., Brath, Ulrika, Akke, Mikael, Palmer, Arthur G.

Journal:

Journal of the American Chemical Society

Année:

2007

Langue:

english

Fichier:

PDF, 106 KB

english, 2007

49

Biosynthetic 13 C Labeling of Aromatic Side Chains in Proteins for NMR Relaxation Measurements

Teilum, Kaare, Brath, Ulrika, Lundström, Patrik, Akke, Mikael

Journal:

Journal of the American Chemical Society

Année:

2006

Langue:

english

Fichier:

PDF, 52 KB

english, 2006

50

Three-dimensional solution structure of calcium-loaded porcine calbindin D9k determined by nuclear magnetic resonance spectroscopy

Akke, Mikael, Drakenberg, Torbjoern, Chazin, Walter J.

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1992